Drug Metabolism Journals

An open access journal of the American Society for Pharmacology and Experimental Therapeutics (ASPET) publishing original research on xenobiotic metabolism, transport and disposition. The term xenobiotic includes therapeutic agents and environmental chemicals. Encourages mechanistic studies of metabolism and transport including genetic variability in expression and regulation of drug-metabolizing enzymes and transporters, using in vivo, in vitro, cultured cells and heterologous expression systems.

Publishes review articles and original research on all aspects of drug metabolism in humans and other species, including the structure, mechanism and regulation of drug-metabolizing enzymes and transporters, drug-drug interactions, pharmacogenetics of metabolism, in silico prediction of metabolic pathways, and the role of metabolism in drug efficacy and toxicity.

Publishes original research and reviews on all aspects of pharmacokinetics, drug metabolism and disposition in animals and humans. Topics include preclinical and clinical pharmacokinetics, in vitro and in vivo absorption-distribution-metabolism-excretion studies, PBPK modeling, drug-drug interactions, transporter-mediated disposition, bioequivalence and population pharmacokinetics.

Publishes papers describing original research and short reports on the metabolism, disposition and fate of xenobiotics in animals and humans. Includes drug-drug interactions, induction and inhibition of drug-metabolizing enzymes, transporter-mediated disposition, pharmacogenetics, in vitro models for predicting human pharmacokinetics, and the role of metabolism in toxicology and therapeutic outcomes.